PROPERTIES OF BACTERIOPHAGES T2 AND T4 WITH UNUSUAL INHERITANCE

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The Nucleic Acids of T2, T4, and T6 Bacteriophages

The deoxyribonucleic acids of the wild type strains of the T(2), T(4), and T(6) bacteriophages have been shown to contain glucose as an integral part of the molecule; the amount of hexose present in each nucleic acid differs. A study of the acid degradation products of the three nucleic acids has revealed that in each instance glucose is linked to the apurinic acid component. In the case of the...

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Infection of Escherichia coli by T2 and T4 bacteriophages as seen in the electron microscope: T4 head morphogenesis.

Bacteriophage T4 capsids seem to be assembled on E. coli protoplasmic membranes. This process seems to involve "lumps" of head protein, which convert to tau particles, which in turn give rise to empty heads. The empty heads leave the bacterial membrane and are then filled with DNA in the central region of the cell. T4 gene 16 and 17 products appear to be necessary for head filling.

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Effect of prophage W on the propagation of bacteriophages T2 and T4.

Studies have been undertaken to determine whether the temperate phage omega present in Escherichia coli strain W is responsible for the inability of this strain to act as a host for T2 and T4. E. coli WS, cured of phage omega, was sensitive to T2 and T4. Lysogenation of E. coli C and WS with phage omega resulted in loss of ability to plate T2 and T4. However, E. coli K-12 lysogens still served ...

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Nucleotides derived from enzymatic digests of nucleic acids of T2, T4, and T6 bacteriophages.

The compositions of the nucleic acids of the T even bacteriophages, T2, T4, and T6 have been shown to be identical with respect to their purine and pyrimidine bases within the accuracy of existing analytical methods for these bases (1). However these viruses contain the unusual pyrimidine, 5-hydroxymethyl cytosine, which provides a unique opportunity for chemical variability in the composition ...

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Isolation of bacteriophages T2 and T4 attached to the outer membrane of Escherichia coli.

Phage T2 or T4 was adsorbed to Escherichia coli, and the outer (L) membrane was then isolated with the phage still attached in their usual postinjection appearance. T2 was readily inactivated by isolated cell walls but very poorly by purified L membrane. T4 was inactivated by neither.

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1956

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.42.8.504